金沢大学附属病院 整形外科

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脊椎外科班

     
     
     
     
臨床研究
 
 現在の学内メンバーは私、出村先生、加藤先生、横川先生のスタッフ4名と清水先生、奥先生、北川先生の院生3名、計7名で頑張っています。獅子奮迅の活躍をしてやつれ果てた(笑)米澤先生が3月いっぱいで浅ノ川総合病院に移動になり、代わりに済生会高岡病院から真っ黒に日焼けした奥先生が脊椎班に加わってくれました。この7名が一つのチームとなって年間約200例の手術をこなし、病棟では18人前後の入院患者を受け持っています。外来は火曜日と木曜日にスタッフ各3名が担当し、1日約50人の患者を診察しています。木曜日の夜には毎週欠かさず医局で症例検討会を行い、手術症例は1例1例を徹底的に全員で検討し適応や術式を決めています。基本的に、脊椎腫瘍を私が担当し、側弯症などの脊柱変形を出村先生、腰痛症、靭帯骨化症を加藤先生が担当しています。困った症例がございましたら是非紹介して頂ければ幸いです。
昨年の脊椎班の最も大きなトピックと言えば、加藤先生の十全医学会賞の受賞と私(村上)の金沢医学館記念医学賞の受賞でしょう。この2つの賞は言わば、金沢大学医学部全体で最も業績を挙げてきた若手と中堅に与えられるような賞で、その2つの賞を整形外科脊椎班が独占したことになります。これは我々脊椎班のこれまでの業績が高く評価された結果と思います。特に加藤先生の受賞した十全医学会賞はこれまで12年間ずっと基礎研究にしか与えられなかった賞ですが、今回初めて臨床研究に与えられました。基礎研究ではない独創的な手術手技の開発に光が当てられ、私も非常に嬉しく思っています
     
 
基礎研究
 
 現在の脊椎班の基礎研究ですが、10名の大学院生(学外6名、学内4名)が中心となってやっています。脊椎班の基礎研究に対する姿勢は常に『臨床で遭遇した疑問を基礎研究で解決する』であり、各院生がそれぞれ難しいテーマに挑戦し頑張っています。厚生連高岡病院の井上先生は、椎体再建におけるcage内骨癒合を脂肪由来幹細胞で促進できないか実験し、現在、論文作成中です。金沢市立病院の太田先生は、当教室で開発されたヨードコーティングscrewを犬の脊椎に挿入し骨伝導能をみる実験をしています。ついに実験が終了し論文を書き始めました。松任石川中央病院の新村先生は、新しい腫瘍脊椎骨全摘術(TES)における液体窒素処理骨のcage内骨癒合を調べ、液体窒素処理骨でもしっかりと骨癒合が得られることを証明しました。すでに論文をPLoS Oneに投稿し結果を待っているところです。金沢医療センターの藤井先生は、龍谷大学理工学部との共同研究で、mobile stabilizationが脊椎固定術に与える影響を力学解析しています。五十嵐先生は、放射線照射が脊椎の骨強度に与える影響を特に骨質に着目して調べています。米澤先生は、新しいTESにおける液体窒素処理骨移植が全身のがん免疫に与える影響を基礎と臨床の両面から調べています。そして、現在、大学に在籍している高橋先生は、加藤先生が開発し特許を取得した体幹運動器具を使って慢性腰痛症に対する運動療法の前向き研究を行っています。清水先生は、脊椎腫瘍進展における硬膜のバリア機構の放射線照射による影響を調べています。奥先生は龍谷大学理工学部との共同研究で骨粗鬆症性脊椎における固定術の力学的解析を始めました。また、理学療法士の黒川先生が脊椎班の院生として、TES患者におけるADLなどの臨床経過を理学療法に着目して詳細にまとめています
     
 
業績
 
英語論文(2010~)
​2017年
  1. Murakami H, Fujimaki Y, Yoshioka K, Kawahara N, Tsuchiya H. Reconstruction using frozen tumour-bearing vertebra en bloc after total spondylectomy. J Orthop Sci 22: 156-159, 2017
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  3. Demura S, Murakami H, Kato S, Yoshioka K, Yonezawa N, Takahashi N, Tsuchiya H. Spontaneous derotation of compensatory lumbar curve after thoracic fusion in adolescent idiopathic scoliosis. Spine Surg Relat Res 1: 27-30, 2017
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  5. Kato S, Murakami H, Inaki A, Mochizuki T, Demura S, Nakase J, Yoshioka K, Yokogawa N, Igarashi T, Takahashi N, Yonezawa N, Kinuya S, Tsuchiya H. Innovative exercise device for the abdominal trunk muscles: An early validation study. PLoS One 12: e0172934, 2017
  6.  
  7. Yoshioka K, Murakami H, Demura S, Kato S, Yokogawa N, Kawahara N, Tomita K, Tsuchiya H. Risk factors of instrumentation failure after multilevel total en bloc spondylectomy. Spine Surg Relat Res 1: 31-39, 2017
  8.  
  9. Yokogawa N, Murakami H, Demura S, Kato S, Yoshioka K, Tsuchiya H. Incidental durotomy during total en bloc spondylectomy. Spine J. 2017 Jul 20. [Epub ahead of print]
  10.  
  11. Yonezawa N, Murakami H, Kato S, Takeuchi A, Tsuchiya H. Giant cell tumor of the thoracic spine completely removed by total spondylectomy after neoadjuvant denosumab therapy. Eur Spine J 26(Suppl 1): 236-242, 2017
  12.  
  13. Sugita S, Murakami H, Yonezawa N, Demura S, Tanaka S, Tsuchiya H. Radical surgery consisting of en bloc corpectomy in recurrence after palliative surgery for spinal metastasis. Spine Surg Relat Res 1: 96-99, 2017
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  15. Rosario M, Takeuchi A, Yamamoto N, Hayashi K, Miwa S, Higuchi T, Abe K, Taniguchi Y, Aiba H, Tanzawa Y, Murakami H, Tsuchiya H. Pathogenesis of Osteosclerotic Change Following Treatment with an Antibody Against RANKL for Giant Cell Tumour of the Bone. Anticancer Res 37: 749-754, 2017
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  17. Rosario MS, Murakami H, Kato S, Fujii M, Yonezawa N, Tsuchiya H. Solitary thoracic intramedullary spinal neurofibroma microsurgically extirpated via recapping T-saw laminoplasty. J Orthop Surg (Hong Kong). 2017 Jan;25(1):2309499017691003
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  19. Kobayashi K, Imagama S, Ando K, Ishiguro N, Yamashita M, Eguchi Y, Matsumoto M, Ishii K, Hikata T, Seki S, Terai H, Suzuki A, Tamai K, Aramomi M, Ishikawa T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Yamada K, Hongo M, Matsuoka Y, Suzuki H, Nakano A, Watanabe K, Chikuda H, Ohya J, Aoki Y, Shimizu M, Futatsugi T, Mukaiyama K, Hasegawa M, Kiyasu K, Iizuka H, Iizuka Y, Kobayashi R, Nishida K, Kakutani K, Nakajima H, Murakami H, Demura S, Kato S, Yoshioka K, Namikawa T, Watanabe K, Nakanishi K, Nakagawa Y, Yoshimoto M, Fujiwara H, Nishida N, Imajo Y, Yamazaki M, Sakane M, Abe T, Fujii K, Kaito T, Furuya T, Orita S, Ohtori S. Risk Factors for Delirium After Spine Surgery in Extremely Elderly Patients Aged 80 Years or Older and Review of the Literature: Japan Association of Spine Surgeons with Ambition Multicenter Study. Global Spine J 7: 560-566, 2017
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  21. Kobayashi K, Imagama S, Ando K, Ishiguro N, Yamashita M, Eguchi Y, Matsumoto M, Ishii K, Hikata T, Seki S, Terai H, Suzuki A, Tamai K, Aramomi M, Ishikawa T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Yamada K, Hongo M, Nishimura H, Suzuki H, Nakano A, Watanabe K, Chikuda H, Ohya J, Aoki Y, Shimizu M, Futatsugi T, Mukaiyama K, Hasegawa M, Kiyasu K, Iizuka H, Iizuka Y, Kobayashi R, Nishida K, Kakutani K, Nakajima H, Murakami H, Demura S, Kato S, Yoshioka K, Namikawa T, Watanabe K, Nakanishi K, Nakagawa Y, Yoshimoto M, Fujiwara H, Nishida N, Imajo Y, Yamazaki M, Sakane M, Abe T, Fujii K, Kaito T, Furuya T, Orita S, Ohtori S. Complications Associated With Spine Surgery in Patients Aged 80 Years or Older: Japan Association of Spine Surgeons with Ambition (JASA) Multicenter Study. Global Spine J 7: 636-641, 2017
     
  22. Imajo Y, Taguchi T, Neo M, Otani K, Ogata T, Ozawa H, Miyakoshi N, Murakami H, Iguchi T. Complications of spinal surgery for elderly patients with lumbar spinal stenosis in a super-aging country: An analysis of 8033 patients. J Orthop Sci 22: 10-15, 2017
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  24. Imajo Y, Taguchi T, Neo M, Otani K, Ogata T, Ozawa H, Miyakoshi N, Murakami H, Iguchi T. Surgical and general complications in 2,961 Japanese patients with cervical spondylotic myelopathy: Comparison of different age groups. Spine Surg Relat Res 1: 7-13, 2017
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  26. Takahashi Y, Kou I, Ogura Y, Miyake A, Takeda K, Nakajima M, Minami S, Kawakami N, Uno K, Ito M, Yonezawa I, Kaito T, Yanagida H, Watanabe K, Taneichi H, Harimaya K, Taniguchi Y, Kotani T, Tsuji T, Suzuki T, Sudo H, Fujita N, Yagi M, Chiba K, Kono K, Sakuma T, Akazawa T, Nishida K, Kakutani K, Shigematsu H, Iida T, Demura S, Hosogane N, Okada E, Nakamura M, Matsumoto M, Watanabe K, Ikegawa S. A Replication Study for the Association of rs11190870 With Curve Severity in Adolescent Idiopathic Scoliosis in Japanese. Spine (Phila Pa 1976). 2017 Sep 8. doi: 10.1097/BRS.0000000000002413.

2016年
  1. Demura S, Murakami H, Kato S, Yoshioka K, Fujii M, Igarashi T, Yonezawa N, Takahashi N, Tsuchiya H. Posterior curve correction using convex posterior hemi-interbody arthrodesis in skeletally immature patients with scoliosis. Spine J 16: 1152-1156, 2016
  2.  
  3. Kato S, Murakami H, Demura S, Nambu K, Fujimaki Y, Yoshioka K, Kawahara N, Tomita K, Tsuchiya H. Spinal metastasectomy of renal cell carcinoma: A 16-year single center experience with a minimum 3-year follow-up. J Surg Oncol 113: 587-592, 2016
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  5. Kato S, Murakami H, Demura S, Fujimaki Y, Yoshioka K, Yokogawa N, Tsuchiya H. The impact of complete surgical resection of spinal metastases on the survival of patients with thyroid cancer. Cancer Med 5: 2343-2349, 2016
  6.  
  7. Kato S, Gasbarrini A, Ghermandi R, Gambarotti, M, Babdiera S. Spinal chordomas dedifferentiated to osteosarcoma: a report of two cases and a literature review. Eur Spine J 25(Suppl 1):251-256, 2016
  8.  
  9. Shinmura K, Murakami H, Tsuchiya H. Second-Generation Total En Bloc Spondylectony (Second-generation TES). In: Landriel FA and Vecchi E. editors. Frontiers in Neurosurgery, Volume 2--[Video Atlas of Spine Surgical Techniques]. Bentham Science Publishers; 2016. p210-224
  10.  
  11. Ishii T, Murakami H, Demura S, Kato S, Yoshioka K, Fujii M, Igarashi T, Tsuchiya H. Invasiveness Reduction of Recent Total En Bloc Spondylectomy: Assessment of the Learning Curve. Asian Spine J 10: 522-527, 2016
  12.  
  13. Sugita S, Murakami H, Kato S, Tanaka S, Tsuchiya H. Disappearance of lung adenocarcinoma after total en bloc spondylectomy using frozen tumor-bearing vertebra for reconstruction. Eur Spine J 25 Suppl 1: 53-57, 2016
  14.  
  15. Kitagawa R, Murakami H, Kato S, Nakada M, Demura S, Tsuchiya H. En bloc resection and reconstruction using a frozen tumor-bearing bone for metastases of the spine and cranium from retroperitoneal paraganglioma. World Neurosurg 90: 698. e1-5, 2016
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2015年
  1. Murakami H, Kawahara N, Tomita K. Primary and Metastatic Tumors of the Spine: Total En Bloc Spondylectomy. In: S.W. Wiesel. editor. Operative Techniques in Orthopaedic Surgery. 2nd edition. Lippincott Williams & Wilkins; 2015. pp2273-2283.
     
    Demura S, Murakami H, Shirai T, Kato S, Yoshioka K, Ota T, Ishii T, Igarashi T, Tsuchiya H. Surgical treatment for pyogenic vertebral osteomyelitis using iodine-supported spinal instruments: initial case series of 14 patients. Eur J Clin Microbiol Infect Dis 34: 261-266, 2015
     
    Demura S, Murakami H, Hayashi H, Kato S, Yoshioka K, Yokogawa N, Ishii T, Igarashi T, Fang X, Tsuchiya H. Influence of Rod Contouring on Rod Strength and Stiffness in Spine Surgery. Orthopedics 38: e520-523, 2015
     
    Kato S, Murakami H, Demura S, Yoshioka K, Hayashi H, Yokogawa N, Fang X, Tsuchiya H. Gradual spinal cord decompression through migration of floated plaques after anterior decompression via a posterolateral approach for OPLL in the thoracic spine. J Neurosurg Spine 23: 479-483, 2015
     
    Yoshioka K, Murakami H, Demura S, Kato S, Tsuchiya H. Prevalence and Risk factors for Development of Venous Thromboembolism after Degenerative Spinal Surgery. Spine (Phila Pa 1976) 40: E301-306, 2015
     
    Yoshioka K, Murakami H, Demura S, Kato S, Tsuchiya H. Mini-open transthoracic approach for resection of a calcified herniated thoracic disc and repair of the dural surface with fibrin glue: a case report. J Orthop Surg (Hong Kong) 23: 243-246, 2015
     
    Yoshioka K, Murakami H, Demura S, Kato S, Kawahara N, Tomita K, Tsuchiya H. Spinal Metastasis from Subcutaneous Sacrococcygeal Ependymoma: A Case Report with Long-Term Follow-Up. Surg J DOI: 10.1055/s-0035-1567878, 2015
     
    Yoshioka K, Matsuda E, Murakami H, Tsuchiya H. Microendoscopic Excision of Osteoid Osteoma in the Pedicle of the Third Lumbar Vertebra. Asian Spine J 9: 958-961, 2015
     
    Sasagawa T, Murakami H, Maruhashi Y, Segawa T, Yamamoto D, Shimizu S, Morita Y, Nakamura T. Iatrogenic Lumbar Vertebral Fracture during Osteosynthesis for a Trochanteric Fracture of the Femur in Diffuse Idiopathic Skeletal Hyperostosis. Asian Spine J 9: 803-806, 2015
     
    Okamoto Y, Murakami H, Demura S, Kato S, Yoshioka K, Hayashi H, Sakamoto J, Kawahara N, Tsuchiya H. The effect of kyphotic deformity due to vertebral fracture - a finite element analysis of a 10 and 20 degree wedge-shaped vertebral fracture model -. Spine J 15: 713-720, 2015
     
    Hayashi H, Murakami H, Demura S, Kato S, Kawahara N, Tsuchiya H. Outcome of posterior lumbar interbody fusion for L4-L5 degenerative spondylolisthesis. Indian J Orthop 49: 284-288, 2015
     
    Hayashi H, Murakami H, Demura S, Kato S, Yoshioka K, Shinmura K, Yokogawa N, Ishii T, Fang X, Shirai T, Tsuchiya H. Surgical site infection after total en bloc spondylectomy: risk factors and the preventive new technology. Spine J 15: 132-137, 2015
     
    Hayashi H, Toribatake Y, Murakami H, Yoneyama T, Watanabe T, Tsuchiya H. Gait Analysis Using a Support Vector Machine for Lumbar Spinal Stenosis. Orthopedics 38: e959-964, 2015
     
    Shinmura K, Murakami H, Demura S, Kato S, Yoshioka K, Hayashi H, Yokogawa N, Igarashi T, Fujii M, Yonezawa N, Tsuchiya H. Implantation of Liquid Nitrogen Frozen Tumor Tissue after Posterior Decompression and Stabilization for Metastatic Spinal Tumors. Asian Spine J 9: 869-875, 2015
     
    Yokogawa N, Toribatake Y, Murakami H, Hayashi H, Yoneyama T, Watanabe T, Tsuchiya H. Differences in gait characteristics of patients with lumbar spinal canal stenosis (L4 radiculopathy) and those with osteoarthritis of the hip. PLoS One 10: e0124745, 2015
     
    Yokogawa N, Murakami H, Demura S, Kato S, Yoshioka K, Hayashi H, Ishii T, Igarashi T, Fang X, Tsuchiya H. Postoperative Cerebrospinal Fluid Leakage Associated With Total En Bloc Spondylectomy. Orthopedics 38: e561-e566, 2015
     
    Yokogawa N, Murakami H, Demura S, Kato S, Yoshioka K, Yamamoto M, Iseki S, Tsuchiya H. Effects of Radiation on Spinal Dura Mater and Surrounding Tissue in Mice. PLoS One 10: e0133806, 2015
     
    Sugita S, Murakami H, Demura S, Kato S, Yoshioka K, Yokogawa N, Tanaka S, Tsuchiya H. Repeated total en bloc spondylectomy for spinal metastases at different sites in one patient. Eur Spine J 23: 2196-2200, 2015
     
    Kimura H, Fujibayashi S, Shimizu T, Otsuki B, Murakami H, Kaido T, Uemoto S, Matsuda S. Successful Total En Bloc Spondylectomy of T7 Vertebra for Hepatocellular Carcinoma Metastasis after Living Donor Liver Transplantation. Spine (Phila Pa 1976) 40: E944-947, 2015

2014年
  1. Murakami H, Kato S, Ueda Y, Fujimaki Y, Tsuchiya H. Reconstruction using a frozen tumor-bearing vertebra in total en bloc spondylectomy can enhance antitumor immunity. Eur Spine J 23 Suppl 2: 222-227, 2014
     
    Murakami H, Demura S, Kato S, Yoshioka K, Hayashi H, Inoue K, Ota T, Shinmura K, Yokogawa N, Fang X, Tsuchiya H. Systemic antitumor immune response following reconstruction using frozen autografts for total en bloc spondylectomy. Spine J 14: 1567-1571, 2014
     
    Murakami H, Tomita K, Kawahara N, Demura S. En Bloc Spondylectomy: Single-Stage Thoracic Spine. In: Ames CP, et al. editors. Spine and Spinal Cord Tumors: Advanced Management and Operative Techniques. QMP/ CRC Press; 2014. p719-734.
     
    Demura S, Tomita K, Kawahara N, Murakami H. Scoring System for Metastatic Tumors: Palliative or Aggressive Resection and Reconstruction. In: Ames CP, et al. editors. Spine and Spinal Cord Tumors: Advanced Management and Operative Techniques. QMP/ CRC Press; 2014. p53-61.
     
    Fujimaki Y, Murakami H, Tomita K, Kawahara N. T-Saw Laminoplasty. In: Ames CP, et al. editors. Spine and Spinal Cord Tumors: Advanced Management and Operative Techniques. QMP/ CRC Press; 2014. p487-495.
     
    Kato S, Murakami H, Demura S, Yoshioka K, Kawahara N, Tomita K, Tsuchiya H. More Than 10-Year Follow-Up After Total En Bloc Spondylectomy for Spinal Tumors. Ann Surg Oncol 21: 1330-1336, 2014
     
    Kato S, Murakami H, Demura S, Yoshioka K, Kawahara N, Tomita K, Tsuchiya H. Patient-reported outcome and quality of life after total en bloc spondylectomy for a primary spinal tumour. Bone Joint J 96-B: 1693-1698, 2014
     
    Kato S, Murakami H, Demura S, Yoshioka K, Hayashi H, Yokogawa N, Fang X, Tsuchiya H. Vertebral Osteomyelitis Caused by Mycobacterium abscessus Surgically Treated Using Antibacterial Iodine-Supported Instrumentation. Case Rep Orthop. 2014; 197061. Epub 2014 Dec 2.
     
    Sasagawa T, Hashimoto F, Nakamura T, Maruhasi Y, Matsumoto N, Segawa T, Yamamoto D, Goshima K, Murakami H, Tsuchiya H. A Pediatric Case of Single-level Idiopathic Cervical Intervertebral Disk Calcification With Symptom Relapse 1 Year After Initial Onset. J Pediatr Orthop 34: 282-286, 2014
     
    Yokogawa N, Murakami H, Demura S, Kato S, Yoshioka K, Hayashi H, Ishii T, Igarashi T, Fang X, Tsuchiya H. Perioperative Complications of Total En Bloc Spondylectomy: Adverse Effects of Preoperative Irradiation. PLoS One 9: e98797, 2014
     
    Yokogawa N, Murakami H, Demura S, Kato S, Yoshioka K, Hayashi H, Ishii T, Fujii M, Igarashi T, Tsuchiya H. Motor Function of the Upper-Extremity after Transection of the Second Thoracic Nerve Root during Total En Bloc Spondylectomy. PLoS One 9: e109838, 2014
     
    Fang X, Murakami H, Demura S, Hayashi K, Matsubara H, Kato S, Yoshioka K, Inoue K, Ota T, Shinmura K, Tsuchiya H. A Novel Method to Apply Osteogenic Potential of Adipose Derived Stem Cells in Orthopaedic Surgery. PLoS One 9: e88874, 2014
     
    Tawara D, Noro K, Tsujikami T, Okamoto Y, Murakami H. Nonlinear mechanical analysis of posterior spinal instrumentation for osteoporotic vertebra: effects of mechanical properties of the rod on the failure risks around the screw. Journal of Biomechanical Science and Engineering 9: 13-00163, 2014
     
    Ito Z, Higashino K, Kato S, Kim SS, Wong E, Yoshioka K, Hutton WC. Pedicle screws can be 4 times stronger than lateral mass screws for insertion in the mid-cervical spine: a biomechanical study on strength of fixation. J Spinal Disord Tech 27(2): 80-5, 2014
     
    Sangadala S, Yoshioka K, Enyo Y, Liu Y, Titus L, Boden SD. Characterization of a unique motif in LIM mineralization protein-1 that interacts with jun activation-domain-binding protein 1. Mol Cell Biochem 385: 145-157, 2014
 
2013年
  1. Tomita K, Kawahara N, Murakami H. Primary and Metastatic Tumors of the Spine: Total En Bloc Spondylectomy. In: J.M. Rhee, S.D. Boden, J.M. Flynn, S.W. Wiesel. editors. Operative Techniques in Spine Surgery. Lippincott Williams & Wilkins; 2013. P212-220.
  2.  
  3. Murakami H, Demura S, Kato S, Nishida H, Yoshioka K, Hayashi H, Inoue K, Ota T, Shinmura K, Yokogawa N, Fang X, Tsuchiya H: Increase of IL-12 following Reconstruction for Total En Bloc Spondylectomy Using Frozen Autografts Treated with Liquid Nitrogen. PLoS One. 8: e64818, 2013.
  4.  
  5. Murakami H, Kato S, Demura S, Yoshioka K, Hayashi H, Inoue K, Ota T, Shinmura K, Yokogawa N, Fang X, Tsuchiya H: Novel Reconstruction Technique Using a Frozen Tumor-bearing Vertebra From a Total En Bloc Sponydylectomy for Spinal Tumors. Orthopedics. 36: 605-7, 2013.
  6.  
  7. Demura S, Murakami H, Kawahara N, Kato S, Yoshioka K, Tsuchiya H: Laminoplasty and pedicle screw fixation for cervical myelopathy associated with athetoid cerebral palsy: minimum 5-year follow-up. Spine 38: 1764-9, 2013.
  8.  
  9. Demura S, Takahashi K, Murakami H, Fujimaki Y, Kato S, Tsuchiya H: The influence of steroid administration on systemic response in laminoplasty for cervical myelopathy. Arch Orthop Trauma Surg. 133: 1041-5, 2013.
  10.  
  11. Demura S, Yaszay B, Carreau JH, Upsani VV, Bastrom TP, Bartley CE, Newton PO: Maintenance of thoracic kyphosis in the 3D correction of thoracic adolescent idiopathic scoliosis using direct vertebral derotation. Spine deformity 1: 46-50. 2013.
  12.  
  13. Demura S, Yaszay B, Bastrom TP, Carreau J, Newton PO, Harms Study Group: Is decompensation preoperatively a risk in Lenke 1C curves? Spine 38: e649-55, 2013.
  14.  
  15. Demura S, Bastrom TP, Schlechter J, Yaszay B, Newton PO, Harms Study Group: Should Postoperative Pulmonary Function be a Criterion that Affects Upper Instrumented Vertebra Selection in Adolescent Idiopathic Scoliosis Surgery? Spine 38: 1920-6, 2013.
  16.  
  17. Kato S, Murakami H, Demura S, Yoshioka K, Ota T, Shinmura K, Yokogawa N, Kawahara N, Tomita K, Tsuchiya H: Patient and family satisfaction with en bloc total resection as a treatment for solitary spinal metastasis. Orthopedics 36: e1424-30, 2013.
  18.  
  19. Kato S, Murakami H, Takeuchi A, Demura S, Yoshioka K, Kawahara N, Tomita K, Tsuchiya H: Fifteen-year survivor of renal cell carcinoma after metastasectomies for multiple bone metastases. Orthopedics 36: e1454-7, 2013.
  20.  
  21. Yoshioka K, Murakami H, Demura S, Kato S, Kawahara N, Tomita K, Tsuchiya H: Clinical outcome of spinal reconstruction after total en bloc spondylectomy at 3 or more levels. Spine 38:E1511-6, 2013.
  22.  
  23. Yoshioka K, Murakami H, Demura S, Kato S, Hayashi H, Inoue K, Ota T, Shinmura K, Yokogawa N, Fang X, Tsuchiya H: Comparative study of the prevalence of venous thromboembolism after elective spinal surgery. Orthopedics. 36: e223-8. 2013.
  24.  
  25. Okayama T, Murakami H, Demura S, Kawahara N, Tomita K, Tsuchiya H. A Biomechanical Study on Laminectomy and Dekyphosis for Thoracic Ossification of the Posterior Longitudinal Ligament. Advances in Mechanical Engineering Vol. 2013, Article ID 928071, 2013
  26.  
  27. Sasagawa T, Hashimoto F, Nakamura T, Maruhasi Y, Matsumoto N, Segawa T, Yamamoto D, Goshima K, Murakami H, Tsuchiya H. A Pediatric Case of Single-level Idiopathic Cervical Intervertebral Disk Calcification With Symptom Relapse 1 Year After Initial Onset. J Pediatr Orthop 34: 282-286, 2013
  28.  
  29. Karasugi T, Nakajima M, Ikari K; Genetic Study Group of Investigation Committee on Ossification of the Spinal Ligaments, Tsuji T, Matsumoto M, Chiba K, Uchida K, Kawaguchi Y, Mizuta H, Ogata N, Iwasaki M, Maeda S, Numasawa T, Abumi K, Kato T, Ozawa H, Taguchi T, Kaito T, Neo M, Yamazaki M, Tadokoro N, Yoshida M, Nakahara S, Endo K, Imagama S, Demura S, Sato K, Seichi A, Ichimura S, Watanabe M, Watanabe K, Nakamura Y, Mori K, Baba H, Toyama Y, Ikegawa S.J: A genome-wide sib-pair linkage analysis of ossification of the posterior longitudinal ligament of the spine. Bone Miner Metab. 31(2): 136-43, 2013.
  30.  
  31. Wong E, Sangadala S, Boden SD, Yoshioka K, Hutton WC, Oliver C, Titus L. A novel low-molecular-weight compound enhances ectopic bone formation and fracture repair. J Bone Joint Surg Am 6;95(5):454-61,2013
 
2012年
  1. Demura S, Kawahara N, Murakami H, Akamaru T, Kato S, Oda M, Tomita K, Tsuchiya H: Giant cell tumor expanded into the thoracic cavity with spinal involvement. Orthopedics. 35: e453-6, 2012. 
  2.  
  3. Ueda Y, Kawahara N, Murakami H, Demura S, Tsuchiya H: Thoracic disk herniation with paraparesis treated with transthoracic microdiskectomy in a 14-year-old girl. Orthopedics. 35: e774-777, 2012.
  4.  
  5. Ueda Y, Murakami H, Demura S, Kawahara N, Tomita K, Tsuchiya H: Eosinophilic granuloma of the lumbar spine in an adult. Orthopedics. 35:e1818-1821, 2012.
  6.  
  7. Kato S, Murakami H, Demura S, Yoshioka K, Okamoto Y, Hayashi H, Tsuchiya H: Epidural inflammatory pseudotumor in the thoracic spine in a patient with polymyalgia rheumatica. Spine J. 12: e1-4, 2012.
  8.  
  9. Kato S, Murakami H, Higashino K, Okada M, Ito Z, Demura S, Kawahara N, Tomita K, Tsuchiya H, Hutton WC.: The effect of spinal shortening after total en bloc spondylectomy: a biomechanical study in the thoracic spine. J Spinal Disord Tech. 25: E183-90, 2012.
  10.  
  11. Kato S, Murakami H, Minami T, Demura S, Yoshioka K, Matsui O, Tsuchiya H: Preoperative embolization significantly decreases intraoperative blood loss during palliative surgery for spinal metastasis. Orthopedics. 35: e1389-95, 2012.
  12.  
  13. Kato S, Murakami H, Demura S, Yoshioka K, Hayashi H, Tsuchiya H: A novel surgical technique for ossification of posterior longitudinal ligament in the thoracic spine. J Neurosurg Spine. 17: 525-9, 2012.
  14.  
  15. Yoshioka K, Kawahara N, Murakami H, Demura S, Matsuda M, Tomita K: A glass foreign body migrating into the lumbar spinal canal: a case report. J Orthop Surg (Hong Kong). 2:257-9, 2012.
  16.  
  17. Sasagawa T, Kunogi J, Masuyama S, Ogihara S, Takeuchi Y, Takeshita Y, Fukushima M, Kamiya N, Murakami H, Tsuchiya H: The clinical utility of a one-shot energy subtraction method for thoracic spine radiography. J Orthop Sci 17: 346-351, 2012.
 
2011年
  1. Kawahara N, Tomita K, Murakami H, Demura S, Yoshioka K, Kato S. Total En Bloc Spondylectomy of the Lower Lumbar Spine: A Surgical Techniques of Combined Posterior-Anterior Approach. Spine (Phila Pa 1976) 36: 74-82, 2011.
  2.  
  3. Demura S, Kawahara N, Murakami H, Abdel-Wanis ME, Kato S, Yoshioka K, Tomita K, Tsuchiya H. Total en bloc spondylectomy for spinal metastases in thyroid carcinoma. J Neurosurg Spine 14: 172-176, 2011.
  4.  
  5. Kato S, Sangadala S, Tomita K, Titus L, Boden S. A LMP-1 Mimetic Compound that Potentiates Bone Morphogenetic Protein-2 Activity in Inducing Transdifferentiation of C2C12 Myoblasts into the Osteoblastic Phenotype. Mol Cell Biochem 349: 97-106, 2011.
  6.  
  7. Kato S, Kawahara N, Murakami H, Demura S, Yoshioka K, Okamoto Y, Tomita K, Tsuchiya H. Extensive thoracolumbar spinal tuberculosis treated with two-stage surgery using a minimally invasive posterior instrumentation. Eur J Orthop Surg Traumatol 21: 407-409, 2011.
  8.  
  9. Sasagawa T, Kunogi J, Masuyama S, Ogihara S, Takeuchi Y, Takeshita Y, Kamiya N, Murakami H, Tsuchiya H. New Computed Radiography Processing Condition for Whole-spine Radiography. Orthopedics 34: e906-910, 2011.
  10.  
  11. Sasagawa T, Kawahara N, Murakami H, Demura S, Yoshioka K, Yamaguchi T, Tsuchiya H, Tomita K. The route of metastatic vertebral tumors extending to the adjacent vertebral body: a histological study. J Orthop Sci 16: 203-211, 2011.
  12.  
  13. Furukawa Y, Hamaguchi A, Nozaki I, Iizuka T, Sasagawa T, Shima Y, Demura S, Murakami H, Kawahara N, Okuyama T, Iwasa K, Yamada M. Cervical pachymeningeal hypertrophy as the initial and cardinal manifestation of mucopolysaccharidosis type I in monozygotic twins with a novel mutation in the alpha-l-iduronidase gene. J Neurol Sci 302: 121-125, 2011.
  14.  
  15. Hayashi Y, Nakada M, Mohri M, Murakami H, Kawahara N, Hamada JI. Ganglioglioma of the Thoracolumbar Spinal Cord in a Patient with Neurofibromatosis Type 1: A Case Report and Literature Review. Pediatr Neurosurg 47: 210-213, 2011.
  16.  
  17. Sakai K, Ono K, Okamoto Y, Murakami H, Yamada M. Cervical flexion myelopathy in a patient showing apparent long tract signs: A severe form of Hirayama disease. Joint Bone Spine 78: 316-318, 2011.
  18.  
  19. Tawara D, Sakamoto J, Murakami H, Kawahara N, Tomita K. Patient-specific finite element analyses detect significant mechanical therapeutic effects on osteoporotic vertebrae during a three-year treatment. J of Biomechanical Science and Engineering 6: 248-261, 2011.
  20.  
  21. Fourney DR, Frangou EM, Ryken TC, Dipaola CP, Shaffrey CI, Berven SH, Bilsky MH, Harrop JS, Fehlings MG, Boriani S, Chou D, Schmidt MH, Polly DW, Biagini R, Burch S, Dekutoski MB, Ganju A, Gerszten PC, Gokaslan ZL, Groff MW, Liebsch NJ, Mendel E, Okuno SH, Patel S, Rhines LD, Rose PS, Sciubba DM, Sundaresan N, Tomita K, Varga PP, Vialle LR, Vrionis FD, Yamada Y, Fisher CG. Spinal instabiliry neoplastic score: an analysis of reliability and validity from the spine oncology study group. J Clin Oncol 29: 3072-3077, 2011.
 
2010年
  1. Tomita K, Kawahara N, Murakami H. Primary and Metastatic Tumors of the Spine: Total En Bloc Spondylectomy. In: S.W. Wiesel. editor. Operative Techniques in Orthopaedic Surgery. Lippincott Williams & Wilkins; 2010. P1846-1854.
  2.  
  3. Kawahara N, Tomita K, Murakami H, Demura S, Yoshioka K, Miyazaki T. Total excision of a recurrent chondrosarcoma of the thoracic spine: a case report of a seven-year-old boy with fifteen years follow-up. Spine 35: E481-487, 2010.
  4.  
  5. Murakami H, Kawahara N, Tomita K, Demura S, Kato S, Yoshioka K. Does interruption of the artery of Adamkiewicz during total en bloc spondylectomy affect neurologic function? Spine 35: E1187-E1192, 2010.
  6.  
  7. Murakami H, Kawahara N, Demura S, Kato S, Yoshioka K, Tomita K. Total en bloc spondylectomy for lung cancer metastasis to the spine. J Neurosurg Spine 13: 414-417, 2010.
  8.  
  9. Murakami H, Kawahara N, Demura S, Kato S, Yoshioka K, Tomita K. Neurological function after total en bloc spondylectomy for thoracic spinal tumors. J Neurosurg Spine 12: 253-256, 2010.
  10.  
  11. Murakami H, Kawahara N, Tomita K. Editorial response. J Neurosurg Spine 13: 412-413, 2010.
  12.  
  13. Murakami H, Kawahara N, Demura S, Kato S, Yoshioka K, Sasagawa T, Tomita K. Perioperative Complications and Prognosis for Elderly Patients With Spinal Metastases Treated by Surgical Strategy. ORTHOPEDICS 33: 165, 2010.
  14.  
  15. Kato S, Kawahara N, Murakami H, Demura S, Yoshioka K, Okayama T, Fujita T, Tomita K. Surgical management of aggressive vertebral hemangiomas causing spinal cord compression: long-term clinical follow-up of five cases. J Orthop Sci 15: 350-356, 2010.
  16.  
  17. Kato S, Kawahara N, Murakami H, Demura S, Shirai T, Tsuchiya H, Tomita K. Multi-Level Total En Bloc Spondylectomy for Solitary Lumbar Metastasis of Myxoid Liposarcoma. Orthopedics 33: 446, 2010.
  18.  
  19. Yoshioka K, Kitajima I, Kabata T, Tani M, Kawahara N, Murakami H, Demura S, Tsubokawa T, Tomita K. Venous thromboembolism after spine surgery: changes of the fibrin monomer complex and D-dimer level during the perioperative period. J Neurosurg Spine 13: 594-599, 2010.
  20.  
  21. Tawara D, Sakamoto J, Murakami H, Kawahara N, Oda J, Tomita K. Mechanical evaluation by patient-specific finite element analyses demonstrates therapeutic effects for osteoporotic vertebrae. J Mech Behav Biomed Mater 3: 31-40, 2010.
  22.  
  23. Tawara D, Sakamoto J, Murakami H, Kawahara N, Oda J, Tomita K. Mechanical Therapeutic Effects in Osteoporotic L1-Vertebrae Evaluated by Nonlinear Patient-specific Finite Element Analysis. J of Biomechanical Science and Engineering 5: 499-514, 2010.